What are suppositories for the treatment of anal fissures?
Rectal suppositories with anti-inflammatory and pain-relieving active ingredients are an effective treatment method to relieve the symptoms of anal fissures as well as a therapeutic approach to support tissue healing after anal fissure surgeries for chronic anal fissures. Rectal suppositories act directly in the affected area and can, depending on the cause of the anal fissure, enable rapid relief of symptoms of anal fissures such as itching or even bleeding.
CANNEFF® SUP suppositories contain a combination of hyaluronic acid and medical CBD (cannabidiol). This patented emulsion matrix with the combination of active ingredients plays an important role in modulating inflammatory processes and has a cell-protective effect. Hyaluronic acid, a natural polysaccharide in the human body, plays a crucial role in regulating moisture in the skin and connective tissue. It can bind enormous amounts of water, thereby supporting the stability and elasticity of tissues and mucous membranes. This unique combination of active ingredients in the CANNEFF® SUP rectal suppositories shows a synergistic effect. The medical CBD optimizes the environment for the effect of hyaluronic acid, while hyaluronic acid maintains the moisture of the mucous membrane, thus supporting healing and pain relief in injuries or inflammations in the rectal area, as well as after colorectal surgeries. Read more here about the unique combination of hyaluronic acid and CBD or about the general treatment of anal fissures.
Which suppositories are recommended for anal fissure?
CANNEFF® SUP suppositories are an innovative medical product that contains medical CBD (cannabidiol) in addition to hyaluronic acid. CANNEFF® SUP rectal suppositories can relieve symptoms of inflammation and fissures in the rectum and accelerate tissue healing. These rectally applied suppositories contain a unique combination of CBD and hyaluronic acid, which can contribute to faster tissue regeneration and healing of an anal fissure. Due to the emulsion matrix, the delivery of hyaluronic acid is increased fivefold (5x) compared to conventional rectal suppositories. It also contains cannabidiol (CBD) of medical quality. Read more here about the effects of CBD and its use in medicine.

What advantages do suppositories offer for anal fissures?
Suppositories offer some advantages in the treatment of anal fissures to relieve the symptoms of anal fissures and to support healing after an anal fissure surgery. Due to their rectal application, they act locally directly at the site of the fissure or inflammation. Suppositories usually work faster because the mucous membranes quickly absorb the active ingredient. Suppositories can contain pain-relieving ingredients that reduce the intense pain in the anal area caused by anal fissures, as well as anal itching as symptoms of anal fissures.
Some suppositories, like CANNEFF® SUP rectal suppositories, even support the regeneration of damaged or inflamed tissue in the anal canal, which can accelerate the healing process. Suppositories are considered a good alternative to tablets and capsules, especially if you have difficulty swallowing larger pills. They can also be easily administered when your general condition is reduced. In cases of nausea or vomiting, they are a good choice because the active ingredient enters the body directly and no side effects occur in the digestive tract.
How do suppositories differ from other topical treatments for anal fissures?
Suppositories offer some essential differences compared to other topical treatments for anal fissures, such as creams, ointments, or gels, which make them particularly suitable for the treatment of anal fissures. The biggest advantage of suppositories lies in their mode of action: they are inserted directly into the anus, allowing the active ingredients to work deeper in the affected anal canal. This form of administration ensures a steady release of the ingredients over a longer period, which can be especially beneficial for hard-to-reach internal anal fissures.
In contrast, creams or ointments are applied externally and primarily act on the surface of the skin around the buttocks. Ointments or creams are often better suited when the anal fissure is near the outer edge of the anus, as they are easier to apply and specifically care for the skin barrier. However, ointments and creams can be less effective deep inside the anal canal because they do not penetrate as deeply into the tissue to the mucosal tears as suppositories do. Another difference is the comfort of use. While suppositories are sometimes perceived as uncomfortable, especially for people who have difficulty inserting them, creams and ointments are generally easier to apply. Ointments with lidocaine can be easily applied to the affected area and often provide immediate pain relief, but only moderately accelerate the healing process. In summary, suppositories are particularly beneficial for anal fissures. In some cases, a combination of both treatment forms, i.e., suppositories and ointments or other medications, can also be useful to promote holistic healing. Medical follow-up care for an anal fissure is also of central importance; be sure to discuss your treatment options with your attending physician. Your doctor can also advise you on further measures to accelerate the healing of the anal fissure. Find more information about medical advice and examination for anal fissures in the blog post Anal Fissure Doctor.
How do I correctly use suppositories to treat anal fissures?
Using suppositories for the treatment of anal fissures and other inflammations in the rectum is straightforward but still requires a certain level of care. Separate a suppository at the perforated spot on the strip. Tear open the packaging by gently pulling it apart and remove the suppository. Insert the suppository, in a comfortable position, with the pointed end first into the rectum. It is recommended to wash your hands before and after insertion for hygiene reasons. Many patients prefer to insert the suppository lying on their side with bent legs. However, you can also choose another position that is comfortable for you. Gently insert the suppository into the anal canal, with the rounded end first. Be careful not to insert the suppository too deeply, only up to the internal sphincter. Hold the position for a few minutes so the suppository stays in place and can dissolve. After inserting the suppository, wash your hands thoroughly again to remove any bacterial residues from the anus. The effect of the suppository usually begins within about an hour.
When using suppositories as part of the treatment of anal fissures, make sure to follow your doctor's instructions or the recommendations on the packaging or leaflet carefully. Do not exceed the recommended dosage. If you have further questions about the application, it is best to consult your doctor or pharmacist. Sharing suppositories is also not recommended. Suppositories usually do not have break lines. Improper handling can cause the suppositories to break and become contaminated.
Can suppositories speed up the healing of anal fissures?
Yes, suppositories can support the healing of anal fissures, especially if they contain special active ingredients like hyaluronic acid and CBD. CANNEFF® SUP rectal suppositories offer targeted local treatment that not only relieves the symptoms of an anal fissure but also supports the healing process of the damaged tissue in the anal area.
Hyaluronic acid is a natural component of the body that plays a key role in regulating moisture in the skin and mucous membranes. In the case of an anal fissure, hyaluronic acid helps to moisturize the damaged anal mucosa by binding water and keeping the tissue elastic and stable. This facilitates the healing of anal tears, as the anal skin can regenerate better and there is less tension on the injured tissue. In addition, hyaluronic acid has anti-inflammatory effects, which can further accelerate healing. CBD is valued in the medical field for its versatile pharmacological properties and complements the effect of hyaluronic acid. CBD influences the body's endocannabinoid system, which plays a role in regulating inflammation, and can thus accelerate the healing process by reducing the inflammatory response in the affected tissue.
The combination of hyaluronic acid and CBD in CANNEFF® SUP suppositories unfolds a synergistic effect. The emulsion matrix in CANNEFF® SUP suppositories increases the release of hyaluronic acid fivefold compared to conventional suppositories, which can lead to faster and more effective healing.
How can CANNEFF® SUP rectal suppositories accelerate healing?
CANNEFF® SUP rectal suppositories, with the combination of hyaluronic acid and CBD, offer an innovative and effective solution to support the healing of anal fissures. The targeted local effect of the suppositories in the anal canal, combined with the anti-inflammatory and healing-promoting properties of the active ingredient matrix, can help the affected anal mucosa regenerate faster and the symptoms of the anal fissure be sustainably and effectively alleviated.
Faster symptom relief of anal fissure: Through the local effect, symptoms such as pain, burning, and anal itching, which are associated with anal fissures, are effectively alleviated.
Promotion of wound healing of mucosal tears: The suppositories not only support the healing of anal fissures, but also promote faster tissue regeneration through the combination of active ingredients.
Improvement of tissue elasticity in the anal canal: Hyaluronic acid improves the elasticity of the tissue and thus ensures that the anal canal remains more flexible, which reduces the risk of recurring anal fissures.

What alternatives to suppositories are there for the treatment of anal fissures?
In addition to suppositories, there are other treatment options for anal fissures. These include certain ointments, creams, as well as special home remedies like chamomile sitz baths. In chronic anal fissures, that is, in severe cases, a surgical procedure called anal fissure surgery may be necessary. Ointments and creams can work similarly to suppositories by locally relieving pain and inflammation in the anal area. A combination of different treatment methods is also possible and should be discussed with your doctor to best support the healing and cleaning of the affected anal area according to your situation. Find further information in the blog post on home remedies for anal fissures, or about the herbal treatment of anal fissures.
Read more here about various alternative therapy approaches for anal fissures or an overview of all therapy options in the blog post on treatment of anal fissures. All information about the examination and diagnosis of anal fissures can be found in the blog post Anal Fissure Doctor.
How can I support the healing of my anal fissure besides using suppositories?
In addition to the treatment of anal fissures with suppositories, there are several measures that can support the healing process of anal fissures. A fiber-rich diet ensures soft stools and thus reduces the strain on the affected anal region. Sitz baths with chamomile or oak bark can have anti-inflammatory effects and promote blood circulation, which can also accelerate the healing process. Also, pay attention to gentle anal hygiene to avoid irritation, and avoid excessive straining during bowel movements. Regular exercise and sufficient fluid intake can also help keep your bowel moving and prevent constipation. Your doctor can also provide you with further specific tips on how to promote the healing of anal fissures and prevent relapses. Read more here about the prevention of anal fissures, or here about measures to accelerate the healing of anal fissures.
What experiences are there with the use of suppositories for the treatment of anal fissures?
Patient reports on the use of suppositories in the treatment of anal fissures provide valuable insights into individual healing processes. Some users report on the CANNEFF® SUP rectal suppositories and mention rapid relief of symptoms such as pain and itching in the anal area, as well as quick healing of the anal fissure.
Especially after surgical procedures, such as an anal fissure operation in cases of chronic anal fissures, some patients report a significant and rapid improvement in their symptoms after the anal fissure surgery. CANNEFF® SUP rectal suppositories can also be used to support the healing process of anal fistulas. Experience reports on CANNEFF® suppositories for anal fissures show that rectal suppositories are a promising treatment option for promoting the healing of mucous membranes and anal tissue in anal fissures. If you do not notice any improvement despite consistent treatment of your fissure, it is advisable to consult your doctor. This way, you can explore alternative treatment options together to accelerate the healing of the anal fissure and support it as best as possible.
How should I properly store suppositories for the treatment of anal fissures?
The suppositories should be stored in their original packaging at room temperature, protected from sunlight, between 2°C and 25°C. Also, keep the suppositories out of reach of children. High temperatures can cause the suppositories to melt. If this happens during hot summer conditions, you can store the suppositories in the refrigerator during these periods. The shelf life of the suppositories is 2 years from production; the expiration date is indicated on the medical product packaging.
What should be considered when dosing suppositories for the treatment of anal fissures?
To support the healing of anal fissures and thus also relieve symptoms of anal fissures, apply 1 suppository daily before going to bed. Depending on the indication to be treated and the type of suppository, the frequency of application may vary. Normally, the rectal suppositories should be used once daily. Your doctor will provide you with more detailed information. To support healing after an anal fissure surgery, also take 1 CANNEFF® SUP rectal suppository daily before going to bed for 20 - 30 days. The duration of use depends on the progress of the treated condition of the anal fissure or the wound healing after surgery but should not exceed 30 days.
For the CANNEFF® SUP rectal suppositories to support the healing of anal fissures, or also healing after anal fissure surgeries, it is recommended to use the suppositories once daily. The suppositories should be inserted into the anus before going to bed. Here you can find further information on the dosage of CANNEFF® SUP rectal suppositories.
How long does it take for suppositories to work against anal fissures?
The effect of suppositories usually begins after 15 to 60 minutes. However, the long-term healing of an anal fissure mainly depends on the severity and stage of the tear in the anus. Even with regular use of suppositories, healing of anal fissures can take several weeks. It may also be advisable to combine different treatment options to speed up the healing of the anal fissure.
Can I combine suppositories with other treatments for anal fissures?
Your doctor can prescribe CANNEFF® SUP rectal suppositories as a supportive treatment for anal fissures to relieve the symptoms of anal fissures and also combine them with other therapeutic approaches. Additionally, CANNEFF® SUP rectal suppositories are often used after colorectal surgery, such as an operation for a chronic anal fissure, to support wound healing following the anal fissure surgery. Suppositories can also help relieve the symptoms of anal fissures and generally promote and accelerate the healing process. By combining different treatment methods, the symptoms of anal fissures can often be relieved more effectively and the healing of the anal fissure accelerated. However, you should always consider combining medications, drugs, medical products, and household remedies for treating anal fissures only after consulting your doctor or pharmacist. This way, you can ensure that there are no unwanted interactions or side effects from the treatment. That means you should clarify any potential interactions with other medications related to the treatment of anal fissures with your doctor in good time before starting the treatment. Find information here about the symptoms of anal fissures, the various causes of anal fissures, and more general information about the different therapeutic approaches within the treatment of anal fissures.
Are suppositories also suitable for women during pregnancy?
Whether suppositories are suitable for the treatment of anal fissures during pregnancy depends on the active ingredients contained in the suppositories. Many over-the-counter suppositories can generally also be used by pregnant women, especially those with natural or mild ingredients. However, there are suppositories that contain active ingredients not recommended during pregnancy, such as certain anti-inflammatory or anesthetic substances and agents.
There is no evidence yet for the safety of CANNEFF® SUP suppositories during pregnancy and breastfeeding, which is why this product is not recommended for use by pregnant or breastfeeding women. Suppositories with CBD should therefore not be used during pregnancy, as there is not yet sufficient research on this.
It is important that pregnant or breastfeeding women always consult their doctor if they experience issues such as anal fissures before using medications, drugs, or medical products. Your doctor can best assess which treatment method is suitable for your individual situation and whether the use of suppositories is the ideal treatment method in your case.
Are suppositories also suitable for preventing anal fissures?
Suppositories are generally used to treat existing anal fissures. For prevention, a high-fiber diet, adequate fluid intake, and gentle anal hygiene are recommended. These measures and many other everyday factors can help keep your stool soft and reduce the likelihood of tears in the anal canal. Find more information here on how to prevent anal fissures.
Can I buy the suppositories for the treatment of anal fissures without a prescription at the pharmacy?
In the pharmacy, you will find both prescription suppositories and non-prescription, freely available medical devices for the treatment of anal fissures. CANNEFF® SUP suppositories are available without a prescription in Austria and can be ordered directly from the webshop.
In Germany, a prescription and pharmacy requirement applies because CANNEFF® SUP rectal suppositories, as a Class 2a medical device, also contain medical CBD (cannabidiol). In Germany, the suppositories are therefore considered prescription medical devices, and your general practitioner or specialist must prescribe CANNEFF® SUP suppositories in Germany by prescription. Consequently, you can only order CANNEFF® SUP suppositories with a prescription through your pharmacy in Germany.